| ncRNA name | MT1JP |
| ncRNA Category | lncRNA |
| ID | 4498 |
| Ensembl | ENSG00000255986 |
| Synonyms | MT1; MTB; MT1J; MT1NP |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB samples and adjacent noncancerous tissues; RB cell lines Y79 and WERI-RB1 |
| Methods | transfection, qRT-PCR, Western blot, MTT assay, transwell assay, cell cycle assay, apoptosis assay, luciferase reporter assay |
| Expression pattern | down-regulated |
| Functional description | We demonstrated that MT1JP was a tumor suppressor by negatively modulating the activity of the Wnt/β-catenin signaling pathway in the development of retinoblastoma and might function as a prognostic biomarker and therapeutic target. |
| PubMed ID | 30024609 |
| Year | 2018 |
| Title | LncRNA MT1JP acts as a tumor inhibitor via reciprocally regulating Wnt/β-Catenin pathway in retinoblastoma. |
| Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.